Salmon genome functional annotation
The genome for Atlantic salmon has been decoded recently, however, the genome currently lack annotation of the sequences that regulate gene expression, including proximal and distal promotors and enhancer elements. Functional annotation requires significant time and cost, and the animal science community has assembled into consortia to tackle the task for livestock genomes (FAANG consortium) and salmonids inside the Functional Annotation of All Salmonid Genomes (FAASG).
There is a paucity of omics data profiling Salmon not subject to an experimental regime designed to elicit specific responses. We plan to perform survey sequencing targeting different tissues at different layers (trascriptome, methylome, regulatome). RNA-Seq, WGBS and ATAC-Seq data will be generated from different salmon tissues as a baseline data independent of experimental manipulation, making it applicable to general studies seeking to understand normal state expression levels across tissues.
The data and analysis in this project are relevant to the emerging FAASG initiative that is seeking to develop a detailed understanding of salmonid genomic elements that drive gene expression and regulation.
The transcriptomic component has been completed and transcriptional landscapes in salmon brain, pituitary gland, ovary and liver have been characterised. This work will be published soon in Frontiers in Genetics.
WGBS and ATAC-Seq data generation are in progress !
There is a paucity of omics data profiling Salmon not subject to an experimental regime designed to elicit specific responses. We plan to perform survey sequencing targeting different tissues at different layers (trascriptome, methylome, regulatome). RNA-Seq, WGBS and ATAC-Seq data will be generated from different salmon tissues as a baseline data independent of experimental manipulation, making it applicable to general studies seeking to understand normal state expression levels across tissues.
The data and analysis in this project are relevant to the emerging FAASG initiative that is seeking to develop a detailed understanding of salmonid genomic elements that drive gene expression and regulation.
The transcriptomic component has been completed and transcriptional landscapes in salmon brain, pituitary gland, ovary and liver have been characterised. This work will be published soon in Frontiers in Genetics.
WGBS and ATAC-Seq data generation are in progress !
